Plant-based Immunomodulators and Their Potential Therapeutic Actions

Immunomodulation is a diverse process by which immunomodulators enhance or suppress immune responses to control disease progression. Immunomodulators are broad class of drugs that include immunosuppressants and immunostimulants. These agents have been used fight against the dysregulated observed during tissue/organ transplantation disorders, such as rheumatoid arthritis, ulcerative colitis, cancers. obtained from myriad plant sources major compounds known medicinal properties for treatment various diseases. However, mechanisms underlying action plant-derived poorly understood. Here, we discuss classes plant-based with examples their effects on signaling pathways, nuclear factor kappa light chain enhancer activated B cells (NF-κB), mitogen-activated protein kinase (MAPK), mammalian target rapamycin pathways. Importantly, preclinical clinical research date understand importance these immunomodulators. Overall, this review highlights significance an alternative therapeutic strategy combating